eFORGE

Description

  eFORGE is the epigenetic equivalent of FORGE, using EWAS rather than GWAS data.


eFORGE identifies tissue or cell type-specific signal by analysing a minimum set of 5 differentially methylated positions (DMPs) for overlap with DNase 1 hypersensitive sites (DHSs) compared to matched background DMPs and provides both graphical and tabulated outputs.


   
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Credits

Breeze CE, Paul DS, Butcher LM, Herrero J, Birney E, Dunham I, Beck S. eFORGE: A tool for identifying tissue-specific signal in epigenomic data. Manuscript in preparation.